This little one-block section of Indiana is actually one-way, but two problems:
1) Speeding vehicles (including a plethora of Muni buses heading back to depot) come through here at ridiculous speeds. Everyone seems to think because this particular block of Indiana is a bit of a long block that it means you can increase your speed to highway rates. The perpendicular parking means it's nearly impossible to back out of a spot without being almost nailed and honked at incessantly. A large apartment complex right there means there are a lot of pedestrians and parking traffic too.
2) This one-way section seems to not mean much to many drivers who come down Indiana and ignore the one-way / dead end sign and simply continue though to pull a u-turn onto the 280 ramp.